Domenii Medical Fibroza chistica

Macroduct - Diagnosticarea fibrozei chisticeWescor - Elitech Group

Specificatii

PRET LA CERERE
Analizorul se comanda separt.

MACRODUCT SWEAT TESTING SYSTEM

The heart of this system is simplicity. The 1959 pad absorption method of Gibson and Cooke, which introduced pilocarpine iontophoresis for sweat stimulation is generally regarded as the reference method for sweat testing. Although generally free of intrinsic error, the method is long and tedious, requires a great deal of technical skill to administer and therefore invites human error. The Macroduct System has forever eliminated the errors inherent in this and many other previously used methods.
The Webster sweat inducer and Macroduct sweat collector produce a pure specimen of eccrine secretion for analysis. The Sweat-Chek analyzer gives a simple and accurate analysis of the specimen. Together as the Macroduct Sweat Analysis System, they have become the world standard, used by thousands of labs worldwide.
Macroduct is approved for sweat collection by the Cystic Fibrosis Foundation, and is rapidly replacing the pad absorption method where laboratories want standardized tests. With the Macroduct system, there is a method of sweat testing that is both accurate and simple.

Sweat Stimulation
The Webster Sweat Inducer is an improved, lightweight unit that accomplishes pilocarpine iontophoresis simply by activating a start switch. It automatically delivers a safe and optimal quantity of pilocarpine for gland stimulation (equivalent to five minutes iontophoresis at 1.5 mA).
The Model 3700 has integral fail-safe circuitry to limit the applied voltage and warn of open circuits. Current is brought up slowly to full power and then reduced slowly at completion of iontophoresis to minimize patient discomfort. Two standard 9-volt batteries supply power.
Pilogel® Iontophoretic Discs are unique gel reservoirs of pilocarpinium ions that are simple and safe to use in the iontophoretic stimulation of sweat. There are no electrolyte solutions to prepare or to keep track of, and no messy electrolyte pads that must be saturated with separate solutions. Instead, a Pilogel disc is inserted into each of the recessed stainless steel electrodes, which are then attached to the patient.

Sweat Collection
The Macroduct Sweat Collector is a unique disposable plastic device having a shallow, concave under-surface. The Macroduct is placed over the iontophoretically-stimulated area on the skin and firmly strapped in place.
Sweat secreted by the sweat glands is forced from the ducts under hydraulic pressure and flows between the skin and the concave undersurface of the Macroduct collector and into the micro bore tubing spiral. A small amount of blue dye allows easy monitoring of the accumulated sweat volume.
After a sufficient volume of sweat has accumulated, a sweat dispenser, or blunt needle on a tuberculin syringe is connected to the open end of the tubing. The tubing is then uncoiled from the body of the Macroduct and severed at the point of attachment. The sample can then be expressed into a supplied sealable micro cup or directly into the analytical instrument.
Sweat production will vary considerably from patient to patient, but the average individual will produce approximately 60 microliters of sweat during a 30-minute collection interval.

Sweat Analysis
The Sweat-Chek Analyzer adroitly performs the analysis phase of Wescor`s sweat testing protocol. Interfacing perfectly with Macroduct, Sweat-Chek measures the total electrolyte of the sweat specimen and displays the reading in equivalent NaCl molarity units (mmol/L). While clinicians have traditionally used sweat chloride or sweat sodium ion assay, total electrolyte concentration has been shown to be an attractive alternative method of sweat analysis. It is a simple and reliable indicator to confirm or exclude the physician`s clinical diagnosis of cystic fibrosis.

• Iontophoresis Current Profiled ramp up and ramp down, equivalent to 1.5 mA for 5 minutes (1.5 mA maximum).
• Current Control: Fail-safe circuitry controlled rate-of-change, circuit fault interrupt and alarm.
• Iontophoresis Electrodes: Stainless steel, recessed and color-coded.
• Power Supply: 2 standard 9-volt batteries (ANSI c18.Im-1992).
• Size and Weight:9.2 cm x 4.5 cm x 15.5 cm; 0.4 kg